Celebrex (celecoxib) belongs to a class of medications called cyclooxygenase (COX) inhibitors. It is used to treat inflammation and pain (inflammation) related to the joints, muscles and tendons in osteoarthritis (arthritis of the tendons), sprains, tendonitis and tendon rupture. It may be used for other conditions as determined by your doctor. Celecoxib may interact with other medications and medicines in the above list, and the details of what medications to avoid while taking it may change your treatment plan. If you are currently taking any other medicine to treat your pain, it is important to inform your doctor about them as soon as possible. Your doctor will need to weigh the potential benefits against the risks before prescribing or using this medication. You should not stop taking this medicine without talking to your doctor first. Some common side effects of this medicine include stomach upset, nausea and vomiting, diarrhea, headache, and flushing.
You should not use this medicine if you are allergic to it or if you have a history of stomach ulcers or other stomach problems.
You should not use this medicine if you are allergic to any medicines, especially aspirin, other NSAIDs, if you are taking any other medications. It is important to inform your doctor if you have a history of asthma or heart disease. You should not stop using this medicine without talking to your doctor first.
This medicine may cause a dangerous drop in blood pressure, which can lead to serious health problems and death. You should call your doctor right away if you have any of the following symptoms: shortness of breath, coughing up blood, or any other form of a blood clot. It is important to tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding.
This medicine may cause a severe drop in blood pressure, which can lead to serious health problems and death. You should tell your doctor if you are currently taking any of the following medicines:
You should call your doctor right away if you have any of the following symptoms:
If you have any of these symptoms, you should immediately contact a doctor. You should not stop using this medicine without talking to a doctor.
This medication may decrease the effectiveness of oral contraceptives. Before taking this medicine, tell your doctor if you are pregnant, plan to become pregnant or are breast-feeding.
It is not known if this medicine passes into breast milk. You should not breast-feed while taking this medicine. You should not stop taking this medicine without talking to a doctor.
Celecoxib, commonly known by its brand name Celebrex, is a nonsteroidal anti-inflammatory drug (NSAID) that is used to relieve pain, reduce inflammation, and in rare cases, combat various conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Its unique formulation, which combines two active ingredients, ibuprofen and naproxen, makes it a preferred choice for many healthcare professionals.
The use of NSAIDs, including Celecoxib, in body pain medications was first discovered by H. W. Peet in the early 1970s at the request of a medical professional. As the stomach contents of Celebrex (ibuprofen)ONDONAbstractAbstractLab-on-Label (Oxford University Press) 2003 Jun;120(10):1059-86
Celecoxib dosage varies by patient and condition. It's crucial to adhere to the recommended dosage guidelines for the shortest possible duration to minimize potential side effects and ensure maximum therapeutic benefit. Dosage adjustments are crucial to minimize the risk of gastrointestinal side effects.
Patients should inform their healthcare provider of any previous NSAID use, especially if they have a history of ulcerative colitis, bleeding disorders, or cardiovascular disease. Additionally, healthcare providers should determine the appropriate dosage based on individual patient needs and medical history.
The appropriate dosage for Celecoxib varies depending on the condition being treated and the severity of the pain. It's crucial to follow the dosage instructions provided by your healthcare provider and to take the lowest effective dose for the shortest possible duration.
Celecoxib should be taken exactly as prescribed by your healthcare provider. It is available in multiple strengths, including 400mg, 800mg, and 800mg tablets. However, it's important to note that Celebrex, like any medication, may have different dosing times for certain conditions or populations.
Patients should maintain open communication with their healthcare provider during treatment to ensure the correct dosing time is reached. It's essential to inform your healthcare provider of any existing medical conditions or medications you're currently taking before starting Celecoxib.
It's also essential to note that Celebrex, like any NSAID, may interact with other medications, including other drugs for pain, supplements, and herbal products. It's crucial to inform healthcare providers about all medications and supplements you're taking to avoid potential interactions.
The most common side effects of Celecoxib include gastrointestinal discomfort, such as nausea, vomiting, and stomach pain. However, some individuals may experience other side effects such as mild skin rash, itching, or hives, which typically resolve on their own without treatment.
It's essential to adhere to the recommended Celecoxib dosage and administration guidelines for shortest possible duration. Consulting with your healthcare provider or pharmacist can help reduce the risk of gastrointestinal side effects and ensure maximum therapeutic benefits.
Celecoxib's unique mechanism of action, similar to other NSAIDs, works by inhibiting the cyclooxygenase enzyme (COX). By inhibiting this enzyme, Celecoxib reduces the production of prostaglandins, which promote inflammation and pain.
Prostaglandins are a type of chemical messenger that plays a crucial role in inflammation and pain. When ingested, they cause inflammation and pain signals through their receptors, leading to inflammation and increased synthesis of prostaglandins.
The prostaglandin receptors in the body are located in various organs, such as the lungs, brain, liver, and kidneys. By binding to these receptors, Celecoxib reduces the synthesis of prostaglandins.
By blocking the activity of COX enzymes, Celecoxib reduces the levels of these chemicals in the body, which promotes the synthesis of prostaglandins and inflammation. This mechanism of action distinguishes Celecoxib from other NSAIDs in that it does not rely on COX-2 inhibition and does not require the presence of other drugs to exert its therapeutic effects.
The appropriate dosage and administration of Celecoxib depend on the condition being treated and the severity of pain. It's crucial to adhere to the recommended Celecoxib dosage and administration guidelines to ensure optimal therapeutic benefit.
Celebrex 100mg Tablet contains the active ingredient Celecoxib. It belongs to the family known as non-steroidal anti-inflammatory drugs (NSAID), and specifically a sub-group known as cyclooxygenase-2 (COX-2) inhibitors. It is used in adults for the relief of signs and symptoms of rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. In conditions like rheumatoid arthritis and osteoarthritis, excess production of prostaglandins by your body can lead to pain and inflammation. Celebrex 100mg Tablet works by decreasing the production of prostaglandins, effectively reducing pain and inflammation.
Do not take Celebrex 100mg Tablet if you are allergic to Celebrex 100mg Tablet or any of its ingredients. Inform your doctor if you had reactions to sulfonamide medicines, suffer from ulcers or bleeding in the stomach or intestines, or experienced adverse reactions to NSAID medications like aspirin.
Before starting the treatment, inform your doctor because it is recommended to not take this medicine if you are pregnant or are breastfeeding. Do not take this medicine if you have severe liver or kidney disease, have inflammatory intestinal conditions, or have heart-related issues such as heart failure, heart disease, or circulation problems. Additionally, if you have had surgeries on leg arteries or have a history of blood circulation problems, this medicine usage should be avoided. Celebrex 100mg Tablet contains lactose. If you are sugar intolerant, consult your doctor before using this product. This medicine is for adults only, it is not for use in children.
Inform your doctor about if you have a history of stomach or intestinal ulcers or bleeding (avoid if currently present), are on acetylsalicylic acid or antiplatelet therapies, use blood clotting or corticosteroid medications, or simultaneously use other non-acetylsalicylic NSAIDs like ibuprofen.
Report your doctor if you have conditions such as smoking, diabetes, high blood pressure, high cholesterol, compromised heart, liver, or kidney function, fluid retention, dehydration, past severe allergic reactions to medications, ongoing infections, or are over 65 years old. Monitoring may be necessary. Notably, Celebrex 100mg Tablet could mask fever or infection signs. Remember, alcohol combined with NSAIDs may increase gastrointestinal risks.
Show Ph priceActive ingredient (involten): Celecoxib is an analgesic, an anti-inflammatory, and pain-relieving active ingredient in non-steroidal anti-inflammatory drugs (NSAIDs), including Celecoxib. It is also used in the relief of signs and symptoms of rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. Celebrex 100mg Tablet works by decreasing the production of prostaglandins, effective at reducing pain and inflammation. It can also lead to good circulation. Therefore, Celebrex 100mg Tablet will not cause gastrointestinal issues but may be used with other forms of treatment without knowing the full effect. It contains lactose. This product is for adults only, it is not for use in children.
Inform your doctor if you have heart failure, heart disease, circulation problems, or are over 65 years old. Celebrex 100mg Tablet could trigger cardiovascular issues. Notably, antiplatelet drugs like aspirin or other blood clotting or corticosteroid medications may increase gastrointestinal risks. Specifically, aspirin or corticosteroid medications may increase stomach bleeding or cause pain in the stomach.
Additionally, Celebrex 100mg Tablet contains lactose for stomach signs and symptoms but lactose for mild mild signs and symptoms. Lactose is a sugar -a common found in food, especially those that are sensitive to fructose. Unlike tablets, it does not contain sulphonamides however sulphonamide oxide is a potent analgesic and antipyretic agent. If you have a history of ulcers or bleeding in the stomach or intestine, develop symptoms such as nausea, stomach discomfort, bloating, or belching, seek medical attention immediately. Consult your doctor before using this product if you have diabetes or kidney disease.
The global celecoxib market is experiencing significant growth, driven by several key factors. As of 2023, the market size was valued at approximately USD 1.64 billion[1][4].
Celecoxib is an effective treatment for managing pain and relieving symptoms associated with various types of arthritis treatment, including:[1-4] It has a similar efficacy profile as well as safety and effectiveness compared to other prescription medications for managing pain. Celebrex, on the other hand, has been shown to be superior to traditional non-steroidal anti-inflammatory drugs (NSAIDs) for relieving pain and inflammation, making the treatment a valuable addition to the medical establishment[4].
Several factors are driving the growth of the celecoxib market:
The celecoxib market can be segmented based on:
Several key applications of the celecoxib market are underway, variety by category and application of the product:
Another segmenting by segmentation is Celecoxib market:
Lastly, theominatral generic versions of celecoxib are approved by the FDA for both short- and long-term use, but their long-term efficacy is still under scrutiny[5].
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